Getting to the Heart of the Matter
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Dr. Cavero is a consultant in the cardiac electrophysiological safety of drugs and an adjunct appointment as Professor, Department of Neurobiology, Pharmacology and Biotechnology, Pharmacy School, at the University of Pisa, Italy. Dr. Cavero has extensive industry experience having directed cardiovascular groups and safety pharmacology departments. He has published more than 185 papers and in recent years his research interests have focused on cardiac electrophysiological safety of pharmaceuticals.
Founder and Scientific Director of Zenas Technologies, Dr. Crumb is the leading expert on cardiac ion channel physiology and pharmacology. He has given numerous presentations, published more than 35 papers and provided reviews for the top industry journals defining the mechanisms and associated risk factors for QT prolongation and investigation of non-hERG currents in cardiac safety. Before Zenas Technologies, Dr. Crumb was an Adjunct Assistant Professor at the Department of Pediatrics, Division of Cardiology at the Tulane University School of Medicine and the Director of Pediatric Clinical Research. Dr. Crumb received Ph.D. in Pharmacology from Tulane University in 1991.
Since retiring from Sanofi Aventis in 2002, Dr. Hock has leveraged his experience as a freelance consultant specializing in Safety Pharmacology. Dr. Hock was a research scientist at Hoechst, Hoechst Marion Roussel and Aventis from 1976 – 2002, where he was ultimately Head of Laboratory for General/Safety. Dr. Hock received his MSc in Neurobiology from the Technical University Darmstadt and his DSc in Zoology form the University Kassel, Department of Biology, Institute of Neuroethology and Biocybernetics. A member of several national and international scientific societies, Dr. Hock is a founding member of “Safety Pharmacology Society”, “Neurowissenschaftliche Gesellschaft e.V.” and “European Behavioural Pharmacology Society.”
Dr. Lucchesi has been a faculty member in the Department of Pharmacology at the University of Michigan for nearly 50 years. He is recognized internationally in the field of pharmacology and has received numerous presitigous awards for his work. Dr. Lucchesi serves as an Editor for the British Journal of Pharmacology and is an editorial board member of many cardiovascular journals. Dr. Lucchesi was elected as a Fellow of the American Heart Association, a Fellow of the International Society for Heart Research and a Fellow of the International Academy of Cardiovascular Sciences.
Dr. Phelps is CEO of a nonclinical consulting firm and has more than 25 years of scientific and drug development experience in the commercial, contract research and pharmaceutical industries with special emphasis in cardiopulmonary safety pharmacology. Previously, Dr. Phelps was Scientific Director of Safety Pharmacology at Allergan, Inc. She has authored publications in cardiovascular toxicity, inhalation toxicology, animal imaging and remote monitoring technologies, ocular pharmacology, and in animal modeling techniques. She obtained her PhD in cardiovascular physiology from the University of British Columbia.
Dr. Shebuski co-manages start-up biotech companies, including Auros, Inc. and has over 25 years experience in the pharmaceutical industry. He established a cardiovascular research consulting firm in 1998 and has served small, mid and large pharma in many aspects of drug discovery and development. Dr. Shebuski is an Adjunct Associate Professor of Pharmacology and Full Professor of Integrative Biology and Physiology at the University of Minnesota Medical School.
Mr. Shubart is a well-respected decision-maker in the pharmaceutical industry's Quality Assurance arena. He has a broad depth of knowledge and experience in GMP, GLP, GCP, Computer Validation and Compliance Audits. Working for multiple pharmaceutical companies for more than 35 years, Mr. Shubart rose to Senior Director of Global R&D Quality Assurance where he managed an international QA staff, created and developed an R&D Computer Validation QA group and, in cooperation with IT colleagues, an engineered approach to software validation. Mr. Shubart is a member of the American Chemical Society and the American Society for Quality where he has been a certified Quality Engineer since 1982.
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