Welcome to CorSolutions where we give you the benefit of our consulting expertise and what we see happening in the industry. We hope this blog helps our clients and potential business colleagues answer some of their pressing cardiovascular discovery and safety pharmacology questions. Please feel free to comment; we welcome your insight as well.
Project teams often ask about the utility of radiotelemetry in cardiovascular studies, where this effective paradigm can be a part of clients’ drug discovery and development plans.
The CorDynamics team has a vast level of expertise in this area. Our laboratories feature dedicated telemetry suites where we conduct studies in six small- and large-animal species. Over [...]
Pulmonary hypertension (PH) is a rare disorder arising from elevated pulmonary blood pressure, usually due to constriction of the pulmonary vasculature.
At CorDynamics, we address pulmonary hypertension as a complex disorder involving consideration of several physiological systems for its study, diagnosis and treatment. Though no single animal model of PH fully mimics its clinical course, together, [...]
This week I’ve been in both Southern California and Western Europe – visiting exclusively with current clients to discuss their ongoing work in our laboratories. What’s interesting was the amount of renewed interest and discussion around very early-stage programs, including those nowhere near ready for GLP safety studies. What a difference from a year ago.
Overall, [...]
My team and I are returning from the 2009 Safety Pharmacology Society meeting in Strasbourg, France. With us was our lead veterinary technician, Ms. Melissa Fisher, who was awarded a Junior Investigator Travel Award for her work with her colleagues developing a model of hypoxic pulmonary vasoconstriction / pulmonary arterial hypertension (PAH) in the cynomolgus [...]
In the last year, exciting breakthroughs in cellular research have crossed the newswires with increasing regularity. The potential of novel treatment modalities, as well as insight into the genesis of numerous pathologies is quite compelling. Within nonclinical safety assessment, scientists are assessing the value of stem cell in vitro assays for predicting drug-induced toxicity.
The following [...]
We’ve recently returned from the 2009 Society of Toxicology meeting in Baltimore. As usual, it was refreshing to catch up with friends, reconnect with previous co-workers, and get the current pulse of our clients.
Other than the scientific topics at hand, the buzz of the convention hall was focused on the current global economic state and [...]
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