February 2, 2010 • Discovery Models
This week I’ve been in both Southern California and Western Europe – visiting exclusively with current clients to discuss their ongoing work in our laboratories. What’s interesting was the amount of renewed interest and discussion around very early-stage programs, including those nowhere near ready for GLP safety studies. What a difference from a year ago.
Overall, [...]
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October 14, 2009 • Pulmonary Hypertension
My team and I are returning from the 2009 Safety Pharmacology Society meeting in Strasbourg, France. With us was our lead veterinary technician, Ms. Melissa Fisher, who was awarded a Junior Investigator Travel Award for her work with her colleagues developing a model of hypoxic pulmonary vasoconstriction / pulmonary arterial hypertension (PAH) in the cynomolgus [...]
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June 9, 2009 • Isolated Perfused Heart
In the last year, exciting breakthroughs in cellular research have crossed the newswires with increasing regularity. The potential of novel treatment modalities, as well as insight into the genesis of numerous pathologies is quite compelling. Within nonclinical safety assessment, scientists are assessing the value of stem cell in vitro assays for predicting drug-induced toxicity.
The following [...]
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April 9, 2009 • Lead Optimization
We’ve recently returned from the 2009 Society of Toxicology meeting in Baltimore. As usual, it was refreshing to catch up with friends, reconnect with previous co-workers, and get the current pulse of our clients.
Other than the scientific topics at hand, the buzz of the convention hall was focused on the current global economic state and [...]
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