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HEMODYNAMICS

At CorDynamics, we leverage our extensive expertise and sophisticated data acquisition platforms to offer advanced hemodynamic measurements.

In addition to measuring heart rate and systemic blood pressure, we have the ability to delve deeper in our assessments. This unique concentration allows us to provide a comprehensive interrogation of test article effect on cardiovascular function.

Left and right ventricular pressures (derivatives)
Blood flow (arterial, venous, skin)
Pulmonary arterial hemodynamics
Cardiac output
Echocardiography
Pressure-volume loop analysis

By including advanced hemodynamic parameters, CorDynamics can uncover or exclude cardiovascular safety issues with lead compounds or backups. In addition, we use these techniques to address preclinical drug discovery heart failure, pulmonary arterial hypertension, thrombosis and ischemia/reperfusion questions.

We can incorporate advanced hemodynamics in all of our models—including isolated Langendorff hearts, along with anesthetized and telemetry subjects. Our skilled technicians have specialized surgical expertise and regularly perform these procedures in our laboratory. Combining this know-how with our robust electrophysiology capabilities, we provide clients with a complete cardiovascular picture.